Frank Brombacher Selected Research

Interleukin-4 (Interleukin 4)

11/2021	Basophil-derived IL-4 promotes cutaneous Staphylococcus aureus infection.
1/2021	Praziquantel Treatment of Schistosoma mansoni Infected Mice Renders Them Less Susceptible to Reinfection.
1/2021	IL-4Rα signaling by CD8α+ dendritic cells contributes to cerebral malaria by enhancing inflammatory, Th1, and cytotoxic CD8+ T cell responses.
1/2021	Myeloid-IL4Rα is an indispensable link in IL-33-ILCs-IL-13-IL4Rα axis of eosinophil recruitment in murine lungs.
1/2021	Interleukin-4 Responsive Dendritic Cells Are Dispensable to Host Resistance Against Leishmania mexicana Infection.
1/2019	Differential Targeting of c-Maf, Bach-1, and Elmo-1 by microRNA-143 and microRNA-365 Promotes the Intracellular Growth of Mycobacterium tuberculosis in Alternatively IL-4/IL-13 Activated Macrophages.
1/2019	Loss of Stat6 affects chromatin condensation in intestinal epithelial cells causing diverse outcome in murine models of inflammation-associated and sporadic colon carcinogenesis.
1/2019	IL-4 Mediated Resistance of BALB/c Mice to Visceral Leishmaniasis Is Independent of IL-4Rα Signaling via T Cells.
12/2018	Deletion of Interleukin-4 Receptor Alpha-Responsive Keratinocytes in BALB/c Mice Does Not Alter Susceptibility to Cutaneous Leishmaniasis.
10/2018	Helminth-induced IL-4 expands bystander memory CD8+ T cells for early control of viral infection.

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Frank Brombacher Research Topics

Disease

82	Infections 01/2022 - 08/2002
38	Inflammation (Inflammations) 01/2022 - 03/2005
17	Asthma (Bronchial Asthma) 01/2021 - 03/2005
12	Tuberculosis (Tuberculoses) 12/2021 - 11/2014
10	Schistosomiasis (Bilharziasis) 01/2022 - 06/2010
9	Hypersensitivity (Allergy) 01/2021 - 02/2004
7	Leishmaniasis 01/2021 - 02/2005
7	Granuloma 01/2021 - 08/2003
7	Cutaneous Leishmaniasis 01/2019 - 03/2011
6	Eosinophilia 01/2021 - 11/2006
6	Respiratory Hypersensitivity 01/2021 - 08/2010
6	Hyperplasia 01/2016 - 11/2006
5	Anemia 01/2021 - 02/2004
5	Necrosis 01/2021 - 10/2013
5	Parasitemia 11/2008 - 02/2004
4	Pneumonia (Pneumonitis) 01/2022 - 04/2016
4	Malaria 01/2022 - 01/2004
4	Disease Progression 01/2021 - 10/2002
4	Colitis 01/2020 - 01/2012
4	Fibrosis (Cirrhosis) 01/2020 - 01/2007
4	Communicable Diseases (Infectious Diseases) 01/2019 - 10/2003
4	Neoplasms (Cancer) 01/2019 - 11/2005
3	Visceral Leishmaniasis (Kala Azar) 01/2019 - 10/2003
3	Nematode Infections 06/2017 - 01/2007
3	African Trypanosomiasis (Nagana) 10/2007 - 11/2002
2	Cryptococcal Meningitis 01/2021 - 02/2009
2	Reinfection 01/2021 - 02/2014
2	Food Hypersensitivity (Food Allergy) 01/2021 - 01/2019
2	Weight Gain 01/2021 - 02/2011
2	Ulcerative Colitis 01/2020 - 01/2012
2	Airway Obstruction (Choking) 01/2020 - 12/2012
2	Metaplasia 01/2020 - 10/2007
2	Liver Cirrhosis (Hepatic Cirrhosis) 01/2019 - 03/2018
2	Dermatitis 01/2016 - 05/2006
2	Bacterial Infections (Bacterial Infection) 01/2015 - 01/2013
2	Hookworm Infections (Hookworm Infection) 12/2014 - 01/2013
2	Hypercholesterolemia 03/2014 - 01/2013
2	Coinfection 02/2014 - 10/2013
2	Cryptococcosis 08/2013 - 10/2007

Drug/Important Bio-Agent (IBA)

42	CytokinesIBA 12/2021 - 11/2002
40	Interleukin-4 (Interleukin 4)IBA 11/2021 - 10/2002
38	Interleukin-13IBA 01/2021 - 10/2002
37	Interleukin-4 Receptors (Interleukin 4 Receptor)IBA 01/2021 - 08/2003
13	InterleukinsIBA 01/2020 - 09/2004
11	Immunoglobulin G (IgG)IBA 01/2021 - 08/2002
10	AllergensIBA 01/2021 - 09/2005
10	Interferon-gamma (Interferon, gamma)IBA 10/2014 - 08/2003
9	AntigensIBA 01/2021 - 10/2006
9	AntibodiesIBA 01/2019 - 08/2002
8	VaccinesIBA 01/2022 - 10/2003
8	Immunoglobulin E (IgE)IBA 01/2021 - 05/2006
8	Proteins (Proteins, Gene)FDA Link 01/2021 - 12/2004
7	InterferonsIBA 12/2021 - 09/2004
7	OvalbuminIBA 01/2020 - 10/2006
6	ChemokinesIBA 12/2021 - 11/2002
6	LigandsIBA 12/2020 - 06/2007
6	Immunoglobulin M (IgM)IBA 01/2020 - 08/2002
6	Interleukin-10 (Interleukin 10)IBA 07/2011 - 02/2004
5	LipidsIBA 01/2022 - 11/2014
5	Pharmaceutical PreparationsIBA 07/2020 - 02/2005
4	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2022 - 09/2020
4	Praziquantel (Biltricide)FDA Link 01/2022 - 01/2020
4	Interleukin-33IBA 01/2021 - 02/2010
4	Interleukin-5 (Interleukin 5)IBA 01/2021 - 02/2003
4	AerosolsIBA 01/2021 - 02/2011
4	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 01/2021 - 01/2004
4	Messenger RNA (mRNA)IBA 01/2017 - 09/2004
4	Interleukin-12 (IL 12)IBA 10/2013 - 09/2004
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2013 - 06/2006
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2007 - 02/2004
3	CollagenIBA 01/2021 - 11/2006
3	Interleukin-6 (Interleukin 6)IBA 01/2021 - 04/2003
3	Docosahexaenoic AcidsIBA 01/2021 - 09/2020
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2019 - 01/2013
3	Transcription Factors (Transcription Factor)IBA 01/2019 - 10/2017
3	STAT6 Transcription FactorIBA 01/2019 - 01/2007
3	CholesterolIBA 01/2016 - 01/2013
3	LipopolysaccharidesIBA 09/2015 - 02/2004
3	Monoclonal AntibodiesIBA 01/2013 - 10/2007
3	Immunoglobulins (Immunoglobulin)IBA 01/2012 - 12/2004
3	ArginaseIBA 05/2010 - 05/2005
3	Interleukin-9 (Interleukin 9)IBA 04/2009 - 01/2005
2	Interleukin-17 (Interleukin 17)IBA 01/2022 - 11/2006
2	NitritesIBA 12/2021 - 01/2021
2	IronIBA 01/2021 - 09/2020
2	Long Noncoding RNAIBA 01/2021 - 01/2018
2	Eicosapentaenoic AcidIBA 01/2021 - 09/2020
2	AlarminsIBA 10/2020 - 01/2019
2	OxazoloneIBA 01/2020 - 01/2012
2	C-Type Lectins (C-Type Lectin)IBA 01/2018 - 03/2005
2	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 04/2014
2	Simvastatin (Zocor)FDA LinkGeneric 01/2016 - 01/2013
2	Muscarinic M3 ReceptorIBA 01/2015 - 01/2007
2	dectin 1IBA 01/2015 - 02/2011
2	SteroidsIBA 01/2015 - 01/2015
2	Hydroxymethylglutaryl CoA Reductases (HMG CoA Reductase)IBA 03/2014 - 01/2013
2	Biological ProductsIBA 10/2013 - 05/2007
2	AutoantibodiesIBA 08/2013 - 02/2005

Therapy/Procedure

16	Therapeutics 01/2022 - 06/2007
5	Drug Therapy (Chemotherapy) 01/2018 - 07/2011